Stress perfusion cardiac MRI with regadenoson and gadofoveset trisodium

Stress perfusion cardiac MRI with regadenoson and gadofoveset trisodium

Background Stress perfusion cardiac MRI (CMR) with a high relaxivity blood-pool contrast agent should allow for improved quantification of myocardial perfusion and myocardium blood volume in patients with coronary artery disease (CAD). In the current study, we sought to evaluate the diagnostic performance and image quality of stress perfusion CMR using the intravascular contrast agent gadofoves...

Regadenoson Cardiac Stress Myocardial Perfusion Scintigraphy

Optimal timing of rest perfusion with regadenoson stress testing - normal volunteer study of quantitative MRI perfusion

Methods Seventeen healthy normal volunteers with Framingham score less than 1% underwent vasodilator stress testing with regadenoson using a SSFP sequence. Rest imaging (Rest 1) was performed initially. Twenty minutes later, regadenoson 400mcg was administered as a 10 second injection with saline flush. Stress imaging was done 70 seconds after the injection. All volunteers received aminophyllin...

Regadenoson stress induced wall motion abnormalities during cardiac MRI

Methods Patients underwent regadenoson CMR that included 3 (basal, mid, apical) slices of rest and peak stress real-time cines, with matching stress and rest first-pass perfusion, and late gadolinium enhancement (LGE) imaging. The reference standard for presence or absence of CAD was derived from invasive coronary angiography or coronary CT angiography (CTA). Invasive angiography established si...

Stress perfusion cardiac MRI in women

Background Cardiac perfusion and stress MRI appear to represent a promising approach for detecting coronary artery disease. It provides valuable information that may not be available from other diagnostic tools such as echocardiography and nuclear cardiology. A recent consensus panel has assigned a Class-II recommendation for the use of myocardial perfusion imaging for the detection of coronary...